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Zhou J., Liu Z., Zhang H., Lei T., Liu J., Zhao Y., Yao Y., Song Q., Oxid Med Cell Longev 2022, 2022, 3921095
Eur Resp J (2020) 56:2001634
Current evidence indicates that ROS are major mediators of tissue injury in MS, promoting OS that disrupts the structural and functional integrity of lipids, proteins, and nucleic acids ( Under pathological conditions, OS-induced disruption of the BBB facilitates the infiltration of inflammatory cells into the CNS, where they release cytokines and other mediators that amplify neuroinflammation, creating a self-perpetuating pathological cycle
