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Description
The primary function of GR is to catalyze the reduction of oxidized glutathione (GSSG) to its reduced form (GSH) using NADPH as an electron donor
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This immunogenicity is further amplified by ferroptosis, driven by bacterial consumption of cysteine and TAK1-HSC70-mediated GPX4 degradation, which results in lethal lipid peroxidation (47)
