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Introduction Selenium has been proposed for the management of thyroid diseases, including Graves disease (GD), Graves Orbitopathy (GO), and chronic autoimmune thyroiditis ( GD is an autoimmune disease with a prevalence of ~1% ( Cell Redox State and Evaluation of Oxidative Stress The balancing of the cell redox state is a key point in cellular homeostasis

10.1016/j.bcp.2017.11.019 Biochem

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Another important aim in regulating ferroptosis during glutamine metabolism is the targeting of Glutaminase 2 (GLS2), a crucial mitochondrial glutaminase that has recently been studied and recognized as a fresh transcriptional objective of p53 [79]