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FIGURE 2 This oxidative stress environment can activate immune signalling pathways promoting neuroinflammation through mitochondrial dysfunction and impaired mitophagy, as observed in recent studies on ASD brains (Pinto Payares et al., 2024)

PARylation can be importantly linked to NRF2 by modulating its stability and function [142], as well as by regulating DNA repair and antioxidant stress responses

Yap1801 complex was crystallized with a 2:1 ratio (protein:precipitant) in a 0.1 M Tris-HCl pH 8.5, 0.28 M lithium sulphate monohydrate, 30% (w/v) PEG 4000 solution at 4 C

Inconsistency in regulatory frameworks and the lack of standards may result in uneven product quality and exaggerated claims