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The absence of symptoms in silent celiac disease can be attributed to the ability of the small intestine to compensate for lost function in the damaged area, but only when the damage is minimal

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They can induce apoptosis, stimulate tumor suppressor genes by resisting DNA methylation modifications, regulate the cell cycle, activate cell survival proteins and modulate epigenetic mechanisms

Early recognition and proper treatment can improve patient's outcome References: [1] Comparative study: Side effects of Folfox4 and folfiri for colorectal cancer chemotherapy regiment in Margono Soekarjo Hospital, Purwokerto Wiratama, I.N.A
