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Aspirin-mediated inhibition of cyclooxygenase (COX)

Non-competitive inhibition happens when exposome components bind to an allosteric site which leads to changing in conformation of enzyme and thereby blocking the drug from binding to it which eventually leads to impairment of drug regardless of its concentration (Si et al., 2009)

Increased prevalence of celiac disease among pediatric patients with irritable bowel syndrome: a 6-year prospective cohort study

10.1016/j.phrs.2005.04.005 [DOI] [PubMed] [Google Scholar] Georgiev, V
