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Poor oral bioavailability is one of the greatest obstacles: curcumin is quickly eliminated in the liver and intestines to glucuronide and sulfate conjugates, which leads to low systemic exposure, short plasma half-life and low tissue penetration [12]
[DOI] [PubMed] [Google Scholar] 28.Duman N., Ersoy Evans S., Atakan N
We further investigated the effect of AnkJ on Dot/Icm-mediated translocation of Ceg14 and found that overexpression of AnkJ significantly inhibited translocation of the TEM1-Ceg14 fusion by the Dot/Icm system (Fig
