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Clin Neurophysiol
Amyloid beta, mitochondrial dysfunction and synaptic damage: Implications for cognitive decline in aging and Alzheimers disease
502,503 These models allow for the rational selection of metabolic inhibitors, pathway-targeting drugs, and immunotherapies that are most likely to be effective against a particular patients CSC profile
Animals that overexpress an osteocalcin-driven igf-1 transgene exhibit higher osteocyte lacunae occupancy, increased bone formation rate (BFR), bone volume and bone mineral density (BMD) but without any change in total osteoblasts or osteoclast numbers
