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While some large prospective cohort studies found that wine drinkers were at lower risk of cardiovascular disease than beer or liquor drinkers (82-84), others found no difference (85-87)

18 No similar improvement was observed in a human trial looking at depression

It is essential for the initial transport of activated long-chain fatty acids across the mitochondrial membrane via the CPT system, thus governing the substrate flux available for both -oxidation and subsequent ketogenesis

This organ then undergoes a metabolic switch to synthesise acylcarnitines, which are transported in plasma to brown adipose tissue to serve as a fuel for thermogenesis