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This suggests that the elevated glutamate concentration following BTZ administration may result from GLAST downregulation

( Antioxidant defense system The evaluation of the non-enzymatic antioxidant glutathione (GSH), along with the enzymatic activities of catalase (CAT), glutathione reductase (GR), and glutathione peroxidase (GPx) in liver tissue, was conducted following established methodologies ( Liver fibrosis Collagen arrangement within the liver was examined utilizing an Olympus BH2 light microscope (Olympus Optical Co., Ltd., Japan), as previously detailed by Oliva et al

However, attention was drawn to the risk of lactation ketoacidosis, which was reported in 1 out of 21 women

Cysteine carbamidomethylation was included as a fixed modification, and methionine oxidation, protein amino-terminal acetylation, deamination of asparagine and glutamine and N-terminal conversion of glutamine to pyro-glutamic acid were included as variable modifications