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doi: 10.3389/fonc.2025.1613751 Received 17 April 2025 Accepted 29 September 2025 Published 24 October 2025 Volume 15 - 2025 Edited by Stefano Cairo, Champions Oncology, Inc., United States Reviewed by Janith Ananda Seneviratne, Peter MacCallum Cancer Centre, Australia Nevim Aygun, Ege University, Trkiye Updates Copyright 2025 Epp, Egan, Poon, Abdul Aziz, Wynne, Chesler, Halasz and Kolch

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Patients should not begin a new cycle of treatment unless the ANC is = 1500 cells/mm3, the platelet count is = 100,000 cells/mm3 and creatinine clearance is = 45mL/min
