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Crosstalk between VEGFR and other receptor tyrosine kinases for TKI therapy of metastatic renal cell carcinoma
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Gravina AG, Pellegrino R, Palladino G, Coppola A, Brandimarte G, Tuccillo C, Ciardiello F, Romano M, Federico A
In another study, exposure of murine glioma stem cells to fractionated radiation induced an increase in IGF-1 secretion and upregulation of IGF-1R, which together conferred resistance by protecting cells from subsequent radiation therapy [143]
