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On the other hand, BRAF -mutant K1 cells with PIK3CA E542K co-mutation exhibited surprising sensitization by RSL3
DSS-induced colitis in mice elicited pronounced symptoms, including reduced locomotor activity, decreased consumption of food and water, dull and lifeless fur, signs of depression-like behavior, huddling behavior, perianal swelling and congestion, diarrhea, bloody stools, and substantial weight loss
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