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A metabolome analysis disclosed that sulphasalazine triggers an increase in the glutamate-derived TCA cycle intermediate -ketoglutarate in addition to a decrease in cysteine and glutathione
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This pattern of metabolic disruption appears to result not merely from chronological aging, but from hormone-driven 'endocrine aging' that destabilizes mitochondrial function
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Cancer Nano
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Global and regional burden of death and disability from peripheral artery disease: 21 world regions, 1990 to 2010
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