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Dose translation from animal to human studies revisited

Glutathione is synthesized by a pathway that starts with homocysteine in the methionine cycle [Figure 1]

doi: 10.1016/j.cccn.2005.04.038 [DOI] [PubMed] [Google Scholar] 70

The advent of genome-wide association technologies has accelerated the discovery of novel polymorphisms, but their interpretation demands a careful accounting of both genetic and nongenetic factorsincluding nutrient status
