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In 2017, it was shown that the enantiomer d-2-hydroxyglutarate (d-2HG) can be used as a functionalized building block for a polyester after cyclization to an allyl containing lactide (Nan and Feher, In medicine, l-2HG is used as a diagnostic biomarker for the characterization of various cancer types (Shim et al., 2014)

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Both are named according to their most characteristic intermediates

87 Coric et al have reported that individuals carrying a combination of the GSTM1-null genotype, active GSTT1, low-activity GSTA1, and variant GSTP1 genotypes exhibited a nine-fold increased risk for renal cell carcinoma compared with those with a reference genotype combination