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Epigenetic Modulators: Peptides that influence histone modification and DNA methylation patterns represent a new class of epigenetic research tools with profound implications for aging biology and disease research

10.1016/j.jconrel.2021.12.032 75 HanZ.SarkarS.SmithA

Under normal conditions, LESs tonic pressure surpasses that of the stomach, effectively preventing the reflux of gastric contents (Reference Mittal, Fisher and McCallum22)

That said, reported side effects include: Common (mild): Nausea (especially oral, usually subsides), mild dizziness, headache during first few days Uncommon: Injection site redness or irritation, temporary fatigue Rare: Hot/cold flashes, changes in blood pressure Theoretical concern: Because BPC-157 promotes angiogenesis, there's a theoretical risk it could support tumor growth in individuals with active cancer