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The approval was backed by data from the CARTITUDE-4 study, where treatment with Carvykti led to statistically significant and clinically meaningful improvement of progression-free survival compared to two standard of care treatment regimens, according to the companies

Research and development of safe and effective anti-obesity pharmacotherapies is urgently needed considering the current obesity epidemic

To investigate the effects of ACore on the A42-induced dendritic spine density, spines were counted along a measured length of dendrite and then normalized by calculating the number of spines per micrometer

To determine which proteoforms may be associated with pathological and cognitive diagnosis on a continuous scale, avoiding subjective between-class limits, parallel linear models were fit with quantification ratio of each peptide as outcome variables, and global cognition Z-score, global pathology Z-score, age at death, sex, post-mortem interval (hours) and number of years in education as explanatory variables