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Description
Uricases - drugs that convert uric acid to allantoin - very limited use due to potential side effects Glossary: Oxidation - Loss of electron during a reaction is called oxidation

Isothiocyanates target Nrf2 and NF-B pathways The figure illustrates that isothiocyanates inhibit NF-B-mediated inflammation and increase the expression of phase II detoxifying and antioxidant enzymes via the Nrf2 signaling pathway
These are necessary for cellular metabolism, energy and cleansing reactions

Under pathological conditions, microgliaas a function of different stimuliare activated to exert neuroprotective effects (M2 phenotype) or to release inflammatory factors and neurotoxic substances (M1 phenotype)
