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Unlike G6PD in males, G6PD in females is more complicated because of the X-linked recessive hereditary pattern and the random inactivation mechanism of X-chromosomes
10.1093/nar/gky893 76 GuX.SunJ.LiS.WuX.LiL
These results indicate that 4-HNE promotes necroptotic signaling by disrupting ubiquitin-dependent degradation of RIP1, leading to its stabilization and activation of the necroptotic cascade (Zhai et al., 2021)
