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Nature 348 , 137143 (1990)
Ng and colleagues synthesized them, added a tyrosine at the start for better stability, and obtained AOD-9604 , Anti-Obesity Drug 9604, the code name of the development program

Retinal ganglion cells express TrkB making them responsive to BDNF signaling critical for survival especially during stress or injury

Among these compounds, GHK-Cu remains one of the most widely studied due to its relationship with cellular signaling, tissue maintenance, and regenerative pathways
