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Curcumin, DMSO, MSM, and serrapeptase are natural pain relievers worth exploring

When the levels of glutamate, an excitatory neurotransmitter, increase in the brain, or when the levels of GABA, an inhibitory neurotransmitter, decrease, the balance is disrupted

Oxcarbazepine, an antiepileptic agent

Most formulations will combine all sizes to get the best of both worlds
