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4-Hydroxy-2-oxoglutarate is hydrolyzed into pyruvate and glyoxylate by 4-hydroxy-2-oxoglutarate aldolase 1 (encoded by the HOGA1 gene)
10.1016/j.bbrc.2020.03.079 27 ChenM.-S.WangS.-F.HsuC.-Y.YinP.-H.YehT.-S.LeeH.-C.et al (2017c)
Importantly, the expression of tumor suppressor protein P53 occurred earlier in the Gstp1/2 / regenerating livers with a sharp induction at 24 and 36 h while in the WT livers its expression mainly detected at 40 and 44 h was much lower
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