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To be specific, after 12-month intensive exercise-based lifestyle intervention, participants with T2DM exhibited a 7% reduction in 8-oxoGuo levels (-0.15 nmol/mmol creatinine [95%CI: -0.27, -0.03]) [176]

While glutathione is naturally present in the body and plays important roles in fetal development, intentional supplementation with injectable forms during pregnancy should only be undertaken under close obstetric supervision if potential benefits clearly outweigh theoretical risks

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