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Acknowledgements Not applicable Abbreviations CMAP Compound motor action potential CNS Central nervous system ECM Cone-extracellular matrix egr-1 gene Early growth response-1 gene EMG Electromyography FAK Focal adhesion kinase GLP Good laboratory practice HNE 4-Hydroxynonenal HPLC High-pressure liquid chromatography JAK-2 Janus kinase 2 LD1 Lethal dose 1 LTB4 Leukotriene B4 MPO Myeloperoxidase MPTP 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine MUP Motor unit potential naB2 Nerve growth factor 1-A binding protein-2 NSAIDs Non-steroid anti-inflammatory drugs SCI Spinal cord injury TXB2 Thromboxane B2 Authors contributions DP, DK, DD, GB, SS, and PS performed the experiments

Product Specifications BPC-157 Peptide Quality Documentation and Lot Testing HPLC Purity Verification (99%) Purity for each released lot is bounded at 99.0% area integration on a reverse-phase HPLC trace recorded at 220 nm

When to extend timeline Consider using beyond 30 days when: Peptide is very expensive (TB-500, pharmaceutical GLP-1s) You're close to finishing vial (only 2-3 doses remain) Peptide appears perfect (clear, no smell, stored optimally) You're using for non-critical purpose (anti-aging vs acute injury) Financial hardship makes wasting difficult Maximum extension: 45 days for most stable peptides (BPC-157, TB-500, semaglutide)