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Pathological expression of CXCL12 at the bloodbrain barrier correlates with severity of multiple sclerosis

doi: 10.1021/acsptsci.0c00081

doi: 10.1186/s13063-019-3792-7

Randomized controlled trials, including CHOIR, CREATE, and the Normal Hematocrit Trial, demonstrated that targeting normal hemoglobin levels in CKD or hemodialysis patients could lead to adverse outcomes, prompting a shift toward lower Hb targets and increased use of RBC transfusions (Szczech et al., 2008
