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Common signs include: Ongoing fatigue or weakness Pale skin Numbness or tingling in the hands and feet Brain fog, forgetfulness, or trouble concentrating Low mood, anxiety, or irritability Poor appetite or digestive upset When B12 is low, your metabolism slows, you have less energy for activity, and appetite signals can get thrown off, all of which make weight loss harder

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Because vitamin B12 has action at the cellular level and is in charge of multiple pathways where a deficiency may lead to the subjective feeling of fatigue or low energy

Howie, D., Ten Bokum, A., Necula, A