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Despite lower basal HER3 expression in KRAS G13D cells, our comparison of isogenic SW48 cell lines harboring different KRAS mutation subtypes revealed that HER2 silencing led to a notable downregulation of HER3 specifically in SW48 G13D cells, along with a significant reduction in p-AKT and p-MAPK levels (Supplementary Fig

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PerR regulons include familiar H 2 O 2 defenses like AhpCF and catalase and the miniferritin Dps, but they do not usually include thioredoxins and glutaredoxins (Sen and Imlay, 2021)