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Description
The resonance assignments were based on chemical shifts
That translates to roughly 35 pounds for a person starting at 220 pounds

Tumor metabolism not only promotes growth but also creates a tumor microenvironment (TME) that inhibits immune effector function by depleting critical metabolites (such as tryptophan, glucose, and glutamine) and generating inhibitory metabolites (such as kynurenine)

Reported side effects have mostly been mild: transient injection-site reactions, occasional headaches, or mild flu-like symptoms