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rebaudiana metabolites effectively prevent experimental liver cirrhosis by modulating NF-B, Nrf2, TGF-, and Smad7 and activating hepatic stellate cells (Ramos-Tovar et al., 2018)
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Cell-cycle synchronization was performed as follows: cells were synchronized at the G1/S boundary using a double-thymidine (2 mM, Sigma) block
