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This makes them valuable for constructing efficient acid labile linkers for antibody-drug conjugates
Intense immunosuppression in chronic progressive multiple sclerosis: the Kaiser study
However, the functional and physiological relevance of class II GRX redox-activity remains unclear
Apoptosis, characterized by chromatin condensation, fragmentation and internucleosomal DNA cleavage, and necrosis, characterized by rupture or fragmentation of the plasma membrane and ATP depletion [32] can coexist and share common pathways, such as involvement of the mitochondria [33]
