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Invited Articles Kopetz S
Depleting myeloid-biased haematopoietic stem cells rejuvenates aged immunity
It addresses why metabolism slows, not just how to force fat loss despite a struggling metabolism
Additionally, environmental stressors like heavy metals and pesticides have been shown in experimental models to impair proteasome function, promote syn aggregation, and drive dopaminergic neuron loss, underscoring the multifaceted contribution of UPS impairment to PD pathogenesis [170]
