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When ferroptosis occurs, inflammation occurs, which exacerbates cell death through the ferroptotic mechanism
It is reported that patients suffering from CAD exhibit heightened chromosomal damage in their peripheral lymphocytes [256]

Nagaraj R, Sharpley MS, Yonggang Zhou Y, Chi F, Braas D, Kim R, Clark AT, Banerjee U, "Nuclear localization of mitochondrial TCA cycle enzymes as a critical step in mammalian zygotic genome activation", Cell, 168 (1-2): 210-223 (2017)

Shen J, Xie P, Wang J, Yang F, Li S, Jiang H, Wu X, Zhou F, Li J
