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However, before an oligodendrocyte can mature and participate in myelination, a complex differentiation process from oligodendrocyte progenitor cell (OPC) must occur

Indeed, tumor cells in the hypoxic microenvironment have elevated demands for glycolysis, in turn, leading to increased lactic acid and acidosis

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Thirdly, the current preclinical studies lack standardized outcome measures, meaning more systematic in vivo studies are required to validate the efficacy and safety of mitochondria-targeted ferroptosis modulators