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The autophagylysosomal pathway serves as a secondary line of defense for degrading misfolded proteins

GHK-Cu is a copper-binding tripeptide commonly referred to as a copper peptide in research contexts

Inflammatory cells are characterized by augmented inflammation-related chemicals including TNF-, IL-1, IL-6 and IL-1, which contribute to inflammation related response such as regulation of chemokines, cytokines and CAMs production

This study compared 60 mg IV edaravone for 6 cycles (24 weeks) with placebo in 137 patients with ALS and successfully met the primary endpoint of adjusted mean difference of ALSFRS-R [140]