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The search strategy, developed according to PRISMA, and Cochrane best practices, encompassed five major databases (PubMed/MEDLINE, Cochrane Library, Google Scholar, ClinicalTrials.gov, and ProQuest) alongside manual searches of key references, grey literature, and clinical trial registries to ensure comprehensive retrieval of both published and unpublished studies

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Route-Specific Pharmacokinetics: Intravenous Route:Peak plasma levels of cyanocobalamin are attained within 1 hour for parenteral doses