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And it's also, I think, our human nature to be like, oh, I want the next best thing that's gonna help me

The FDA cited three concerns: potential immunogenicity (the peptide could trigger immune reactions), manufacturing impurity risks (synthetic peptides can contain truncated sequences and other contaminants), and a lack of human safety data sufficient to evaluate risk

The general principle is that route follows volume and the compounds absorption profile larger volumes and compounds intended for rapid systemic uptake lean toward IM

Official guidance from the Food and Drug Administration and Pfizer-BioNTech state that the two doses should be administered 21 days apart based on the results of clinical trials