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[DOI] [PMC free article] [PubMed] [Google Scholar] 180.Zwolak I., Gobiowska D
Wu C-C, Chen M-S, Cheng Y-J, et al

Dysregulation of CYP51A1 activity may contribute to tumor progression by altering apoptotic sensitivity and shaping an immunosuppressive tumor microenvironment

This pathway relies on an intracellular domain, TIRAF, which recruits adapter proteins such as MyD88, triggering NF--regulated genes and modulating inflammatory responses (Zheng et al., 2019