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doi: 10.1016/j.atherosclerosis.2009.06.002

Serum analysis of 32 patients with high-frequency migraine revealed abnormally low levels of alpha-lipoic acid (ALA) and lactate, along with abnormally high levels of peroxides in 46.9% of the patients, further supporting the role of oxidative stress and metabolic alterations in the pathophysiology of migraine (40)
Additionally, as previously discussed, there is a possibility that the combination of a statin in addition to PCSK9 inhibitors may have enhanced potential in the management of dyslipidemia compared to either therapy alone
