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Insulin receptor signaling in cones

AIS patients exhibit a high prevalence of electrocardiographic abnormalities, with study reporting incidence rates exceeding 90%, primarily manifesting as ST-segment elevation/depression, QTc prolongation, and AF (271)

PM2.5 exposure triggers cell death through lysosomal membrane permeabilization and leads to ferroptosis insensitivity via the autophagy dysfunction/p62-KEAP1-NRF2 activation in neuronal cells