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These finding are corroborated by Mummichog analysis, which showed substantial dysregulation of pathways involved in the metabolism of amino acids/secondary metabolites and glyoxylate/dicarboxylate in both the supernatant and cellular extract fractions (Fig

241 The oscillation of NAD + , in turn, coordinates the transcription and behavior through the circadian clock

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Production of reactive oxygen species (ROS) was monitored following 5-(and-6)-chloromethyl-2,7-dichlorodihydrofluorescein diacetate acetyl ester and MitoSOX Redderived fluorescence