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Statistical parameters were calculated using the Design Expert program version (13.0.5.0, Stat-Ease Inc., USA) (Singh et al

What the published research reported A phase-2 randomized trial published in the New England Journal of Medicine in 2023 studied retatrutide in adults with obesity and reported substantial, dose-dependent reductions in body weight over 48 weeks, alongside a gastrointestinal side-effect profile broadly similar to other incretin drugs

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During pregnancy and lactation, even natural substances can affect: Fetal development Placental function Breast milk composition Since research is limited, no supplement can be declared fully safe unless studied in pregnant or breastfeeding women specifically