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This procedure is preferred to the use of washed acid precipitated proteins as we noted that, after restoring neutral pH, the presence of a massive amount of denatured hemoglobin induces oxidation of the reducing agent used to detach GSH from GSSP, hampering a precise and accurate measurement of GSSP

Plant J 50:347363

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At higher doses (515 mg/kg), animal studies have shown a reduction in dopaminergic neurons in the substantia nigra and striatum, suggesting potential neurotoxicity that may impair motor and cognitive functions [141,142]