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Defining and measuring recovery from myalgic encephalomyelitis and chronic fatigue syndrome: the physician perspective

Enzymes from the TET and JMJ family catalyse histone and DNA demethylation and they are inhibited by the accumulation succinate, the by-product of these enzymes

doi: 10.1159/000264677 173 ChenXZWangRChenHNHuJK

Unlike other known types of cell death, including necroptosis, pyroptosis, autophagy, and ferroptosis, cuproptosis results from Cu-mediated mitochondrial proteolipid acylation, causing DNA damage, lipid dysregulation, mitochondrial structural abnormalities, and dysfunction, ultimately leading to cell death ( Table 1 )