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after clinical and laboratory investigation of the patient, the diagnosis of Reye's syndrome was given, as ASA is associated with such a syndrome, with the switch from ASA to clopidogrel, in one initial dose of 1 mg/kg per day, in order to maintain the antiplatelet activity

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[PUBMED Abstract] Molven A, Grimstvedt MB, Steine SJ, et al.: A large Norwegian family with inherited malignant melanoma, multiple atypical nevi, and CDK4 mutation