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Antioxidants (Basel) 9: 779, 2020

Recent preclinical data indicate that intermittent or adaptive dosing schedules significantly prolong therapeutic effectiveness compared to continuous drug administration by disrupting metabolic and epigenetic adaptations critical for DTP survival (Kruk and Schwalbe, 2006

Certain conditions may blunt or impede therapeutic response to methylcobalamin therapy
H.et al (2017a)
