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In a placebo-controlled trial in 34 healthy individuals, consuming yogurt fortified with 10 billion CFUs of Bifidobacterium animalis subspecies lactis plus 600 mg of the amino acid arginine (a precursor to nitric oxide) daily for 12 weeks improved vascular function and was therefore suggested to reduce atherosclerosis risk

This simplified structure of 4 codes replaces 13 codes used previously, as follows: Associated imaging codes that have been replaced are 75962, 75964, 75966, 75968 and 75978

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The molecules are large (polymeric DNA fragments ranging from kilodaltons into the megadalton range), highly polar, and have no realistic path across intact stratum corneum