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Prepare by hydrating, resting well, and avoiding heavy foods pre-tour

The complex travels through the small intestine until it reaches the terminal ileum, where specialised receptors called cubam (a complex of cubilin and amnionless proteins) recognise and facilitate the uptake of the B12-IF complex into enterocytes (intestinal cells)

Table 1: Medicines reported to be associated with gynaecomastia [this is not an exhaustive list] 2-7 *Classification of quality of evidence for strength of medicine associations with gynaecomastia

Store in a cool, dry, secure and sterile environment away from any unauthorised persons or children