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Collectively, glutamine-derived metabolites act as epigenetic modulators in a wide range of cell and tissue types, including various types of cancer cells, stem cells, immune cells, and even adipocytes

The endometrium is structured into two layers of cells, mesodermal-derived glandular and luminal epithelium over a connective tissue specified as stroma

Although the bleeding risk and the necessity of platelet transfusion increase with the increase of CIT grade, there are still a few observational studies that have evaluated the relationship between thrombocytopenia and cancer types and chemotherapy regimens according to CTCAE grade