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No completed human clinical trials exist for native MOTS-c
Liu X, Wang T, Wang W, Liang X, Mu Y, Xu Y, et al

Due to its electrical polarity, Hg 2+ poorly crosses the plasma membrane or the blood-brain and placental barriers

[DOI] [PMC free article] [PubMed] 145.Livingston NR, Kiemes A, Devenyi GA, Knight S, Lukow PB, Jelen LA, et al
